Vitamin B6 EP Impurity A

Vitamin B6 EP Impurity A - Names and Identifiers

Name	1,3-dihydro-6-methylfuro[3,4-c]pyridin-7-ol
Synonyms	Vitamin B6 EP Impurity A Pyridoxine Cyclic Ether IMpurity 6-Methyl-1H,3H-furo[3,4-c]pyridin-7-ol 6-Methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol 1,3-dihydro-6-methylfuro[3,4-c]pyridin-7-ol 3-methyl-8-oxa-4-azabicyclo[4.3.0]nona-1,3,5-trien-2-ol
CAS	5196-20-3
EINECS	225-981-4

Vitamin B6 EP Impurity A - Physico-chemical Properties

Molecular Formula	C8H9NO2
Molar Mass	151.16256
Density	1.286±0.06 g/cm3 (20 ºC 760 Torr)
Boling Point	358.5±42.0 °C(Predicted)
Appearance	morphology neat
pKa	5.49±0.20(Predicted)
Storage Condition	2-8°C

Vitamin B6 EP Impurity A - Risk and Safety

UN IDs

UN 2811 6.1 / PGIII

Vitamin B6 EP Impurity A - Upstream Downstream Industry

Raw Materials

Furo[3,4-c]pyridine, 1,3-dihydro-6-methyl-4,7-bis(trimethylsilyl)-
5-butoxy-4-methyl-1,3-oxazole
Silane, trimethyl[3-(2-propynyloxy)-1-propynyl]-
DIPROPARGYL ETHER
2,5-Dihydrofuran
5-Ethoxy-4-methyloxazole
Pyridoxine

Vitamin B6 EP Impurity A - Introduction

1,3-dihydro-6-methylfuro[3,4-c]pyridin-7-ol is an organic compound with the molecular formula C10H11NO2. Its nature, use, preparation and safety information are described below:

Nature:
1,3-dihydro-6-methylfuro[3,4-c]pyridin-7-ol is a white solid with a distinctive odor. It is soluble in organic solvents such as ethanol, dimethylformamide and chloroform, and insoluble in water.

Use:
1,3-dihydro-6-methylfuro[3,4-c]pyridin-7-ol has a wide range of applications in the field of medicine. It is an important intermediate that plays a key role in the synthesis of drugs. It is often used to synthesize biologically active compounds, such as anti-cancer drugs and anti-inflammatory drugs.

Method:
1,3-dihydro-6-methylfuro[3,4-c]pyridin-7-ol can be prepared by a variety of methods, one of which is commonly used by chemical synthesis. The specific method is that the Furo [3,4-c] pyridine compound is condensed with an appropriate formaldehyde derivative under acidic conditions, followed by reduction and decarboxylation to obtain the target product.

Safety Information:
The safety information about 1,3-dihydro-6-methylfuro[3,4-c]pyridin-7-ol is not very detailed. As an organic compound, it may have certain toxicity and irritation. When using, should follow the correct experimental operation method, avoid direct contact with the skin and inhalation of dust or steam. It should be used in a well-ventilated place as much as possible to ensure safety.

Last Update：2024-04-09 21:54:55